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editing with engineered nucleases - Prometheus IP

by Yamini Asthana  June 8, 2015

Genome editing, also referred to as genome editing with engineered nucleases (GEEN) is a category of genetic engineering, in which DNA is inserted, replaced, or removed from a genome using artificially engineered nucleases, or “molecular scissors.” The nucleases create specific double-stranded break (DSBs) at desired locations in the genome, and harness the cell’s endogenous mechanisms...

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